InvivoGen provides a collection of monoclonal (mAb) and polyclonal (pAb) isotype control antibodies designed for use as negative controls. The mAbs are produced in Chinese hamster ovarian (CHO) cells or hybridomas. A pAb isotype control purified from rat sera is also available. These isotype controls should be matched to the primary antibody's host, isotype and method of production. They should be used at the same working concentration as the primary antibody under identical experimental conditions.