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Anti-hCD20-hIgG1

Anti-hCD20-hIgG1 Unit size Cat. code Docs Qty Price
Human CD20 (rituximab) antibody - Human IgG1
100 µg
hcd20-mab1
+-
$299.00

Monoclonal human IgG1 antibody against human CD20

Anti-hCD20-hIgG1 features the constant region of the human IgG1 isotype and the variable region of rituximab.

Rituximab is a mouse/human chimeric monoclonal antibody that targets the CD20 antigen found on the surface of malignant and normal B lymphocytes.

Binding of rituximab to CD20 results in cell destruction through different mechanisms including direct signaling of apoptosis, complement activation and cell-mediated cytotoxicity.

Rituximab has been approved by the FDA for the treatment of various lymphoid malignancies, including B-cell non-Hodgkin's lymphoma and B-cell chronic lymphocytic leukaemia.

Anti-hCD20-hIgG1 was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography with protein G.

 

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Specifications

Clonality: Monoclonal antibody

Specificity: Targets cells expressing human CD20

Isotype: Human IgG1

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Contents

100 µg purified anti-hCD20-hIgG1 antibody, provided azide-free and lyophilized.

Product is shipped at room temperature.

Store lyophilized antibody at -20°C.

Lyophilized product is stable for 2 years

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Citations

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