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Cell Culture

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PRR Ligands

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Light and Heavy Chain Plasmids

pFUSE Collection
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Light and Heavy Chain Plasmids

pFUSE Collection
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Fc-Fusion Vectors

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pFUSEN-Lucia Vectors
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Cloning and Expression Plasmids
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SARS-CoV-2 Related Genes

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Ubiquitous Promoters
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Research Fields

PRR signalings
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TiGer Tet-on System

PRR signalings

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Cyclic dinucleotide (CDN) sensor - STING
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Inflammasomes

IL-1β/IL-18 Sensor Cells
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Regulated Cell Death

Cell Death Detection
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Immunotherapy

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Vaccination

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Antibody Engineering

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Toll-Like Receptors

TLR Reporter Cells
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NOD-Like Receptors

NOD Cell Lines
NOD Ligands
NOD Genes

RIG-I-Like Receptors

RLR Genes
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RLR Reporter Cells

C-type Lectin Receptors

CLR Reporter Cells
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Cytosolic DNA Sensing

Cytosolic DNA Sensing Reporter Cells
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Cyclic dinucleotide (CDN) sensor - STING

STING Reporter Cells
STING Ligands
STING Gene Variants

Immune Checkpoints (IC)

Biosimilar Immune Checkpoint mAbs
IC-expressing Cell Lines
Immune Checkpoint Cellular Assays
Immune Checkpoint Genes
Mouse in vivo Antibodies

Antibody Drug Conjugates (ADCs)

Antibodies for Conjugation
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Light and Heavy Chain Plasmids

pFUSE Collection
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Human monocytes

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#Cell Lines

Human NLRP3-KO THP-1 Cells

NLRP3-KO monocytes

Validation of NLRP3 KO in THP1-KO-NLRP3 cells

Absence of mature IL-1β secretion in THP1-KO-NLRP3 cells

Absence of pyroptosis in THP1-KO-NLRP3 cells (LDH read-out)

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Human NLRP3-KO THP-1 Cells