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Cell Culture

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HT29 Cell Lines
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PRR Ligands

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Light and Heavy Chain Plasmids

pFUSE Collection
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Light and Heavy Chain Plasmids

pFUSE Collection
pTRIOZ Collection

Fc-Fusion Vectors

C-terminal
pFUSE-Fc Vectors
pINFUSE-Fc Vectors
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pFUSE-Lucia-Fc
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N-terminal
pFUSEN-Fc Vectors
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pFUSEN-Lucia Vectors
Engineered Fc pFUSEN-Lucia-Fc Vectors

Expression Plasmids

Cloning and Expression Plasmids
pMONO
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pVIVO
Gene and Promoter Collections
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pDRIVE

SARS-CoV-2 Related Genes

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Ubiquitous Promoters
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Research Fields

PRR signalings
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COVID-19
TiGer Tet-on System

PRR signalings

Toll-Like Receptors
NOD-Like Receptors
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C-type Lectin Receptors
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Cyclic dinucleotide (CDN) sensor - STING
Aryl Hydrocarbon Receptor
Cytosolic Sugar Sensors (ALPK1 & TIFA)
dsRNA Receptors

Inflammasomes

IL-1β/IL-18 Sensor Cells
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Regulated Cell Death

Cell Death Detection
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Immunotherapy

Immune Checkpoints (IC)
Antibody Drug Conjugates (ADCs)

Vaccination

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Autophagy

Autophagy Reporter Cells
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Antibody Engineering

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Cytokines

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Toll-Like Receptors

TLR Reporter Cells
TLR Ligands
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NOD-Like Receptors

NOD Cell Lines
NOD Ligands
NOD Genes

RIG-I-Like Receptors

RLR Genes
RLR Ligands
RLR Pathway Inhibitors
RLR Reporter Cells

C-type Lectin Receptors

CLR Reporter Cells
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Cytosolic DNA Sensing

Cytosolic DNA Sensing Reporter Cells
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Cyclic dinucleotide (CDN) sensor - STING

STING Reporter Cells
STING Ligands
STING Gene Variants

Immune Checkpoints (IC)

Biosimilar Immune Checkpoint mAbs
IC-expressing Cell Lines
Immune Checkpoint Cellular Assays
Immune Checkpoint Genes
Mouse in vivo Antibodies

Antibody Drug Conjugates (ADCs)

Antibodies for Conjugation
Conjugatable PRR Ligands

Light and Heavy Chain Plasmids

pFUSE Collection
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Human monocytes

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#Cell Lines

Human NLRP3-KO THP-1 Cells

NLRP3-KO monocytes

Validation of NLRP3 KO in THP1-KO-NLRP3 cells

Absence of mature IL-1β secretion in THP1-KO-NLRP3 cells

Absence of pyroptosis in THP1-KO-NLRP3 cells (LDH read-out)

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Human NLRP3-KO THP-1 Cells