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Endosomal Acidification Inhibitor - Autophagy Inhibitor
Bafilomycin A1 is a known inhibitor of the late phase of autophagy.
Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes .
Bafilomycin A1 acts by inhibiting vacuolar H+ ATPase (V-ATPase).
1. Yamamoto A. et al., 1998. Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H- 4-II-E cells. Cell Struct Funct. 23(1):33-42.Back to the top
Working Concentration: 0.1 - 1 μM
CAS number: 88899-55-2
Molecular weight: 622.83
Solubility: 0.1 mg/ml in DMSO or ethanolBack to the top
Bafilomycin A1 is provided as a solid.
- 10 µg Bafilomycin A1
Bafilomycin A1 shipped at room temperature.
Store at -20 ̊C.
Solid product is stable 1 year at -20°C.Back to the top