TLR7/8 Ligands

Toll-like receptor (TLR) 7 and TLR8 play an important role in the immune response to viral infection. They recognize single stranded RNAs as their natural ligand and also small synthetic molecules such as imidazoquinolines and nucleoside analogs.

InvivoGen provides the most comprehensive choice of ligands known to activate TLR7/8. For vaccination studies, InvivoGen supplies the TLR7/8 ligands, Gardiquimod, Imiquimod and R848 (resiquimod) VacciGrade™ (preclinical grade: sterile and endotoxin level

The functionality and specificity of these TLR ligands are validated using HEK-Blue™ TLR7 and HEK-Blue™ TLR8 Cells.

Disclaimer: Our products are provided for research purpose only. Commercial applications may require licensing from third parties.
Note that the sequence of available ORFs provided by InvivoGen can differ from a given reference Genbank record due to genetic variations and/or alternative splicing. Customers should verify that the version of a gene sold by InvivoGen is suitable for the customer needs.
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