NOD1/NOD2 Agonists

NOD1 (CARD4) and NOD2 (CARD15) are two members of the growing family of Nod-like receptors (NLRs, also known as CATERPILLER), characterized by a nucleotide-oligomerization domain (NOD) and ligand-recognizing leucine-rich repeats. NOD1 and NOD2 are involved in the recognition of peptidoglycan (PGN), major surface component of Gram-positive bacteria.

InvivoGen provides ligands that activate both NOD1 and NOD2 such as PGNs and M-TriDAP, a PGN degradation product.
The functionality of these NOD1/NOD2 ligands is validated using HEK-Blue™ NOD1 and HEK-Blue™ NOD2 Cells.

M-TriDAPNOD1/NOD2 Agonist - MurNAc-L-Ala-gamma-D-Glu-mDAP - PGN-like molecule1 mg
PGN-ECndi ultrapureNOD1/NOD2 Agonist - Insoluble peptidoglycan from E. coli K125 mg
PGN-ECndss ultrapureNOD1/NOD2 Agonist - Soluble sonicated peptidoglycan from E. coli K121 mg
PGN-SAndi ultrapureNOD1/NOD2 Agonist - Insoluble peptidoglycan from S. aureus5 mg
Disclaimer: Our products are provided for research purpose only. Commercial applications may require licensing from third parties.
Note that the sequence of available ORFs provided by InvivoGen can differ from a given reference Genbank record due to genetic variations and/or alternative splicing. Customers should verify that the version of a gene sold by InvivoGen is suitable for the customer needs.
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