PRR Ligands & Cytokines
InvivoGen provides an extensive set of tools to study the innate immune system and in particular a comprehensive collection of the pathogen-associated molecular patterns (PAMPs). PAMPS are recognized by pattern recognition receptors (PRRs). Five families of PRRs have been shown to initiate proinflammatory signaling pathways: Toll-like receptors(TLRs), NOD-like receptors (NLRs), RIG-I-like receptors (RLRs), C-type lectin receptors (CLRs) including Dectin-1, cytosolic dsDNA sensors (CDSs) and NLRs involved in the formation of inflammasomes. We provide ligands to activate these receptors, NF-κB activators and a selection of cytokines.