C-type Lectin Receptors - CLRs
C-type lectin receptors (CLRs) comprise a large family of receptors that bind to carbohydrates in a calcium-dependent manner. CLRs include Dectin-1, Mincle, DC-SIGN, DC-SIGNR and MBL. These CLRs share one or more CRD (carbohydrate-recognition domains). These receptors are involved in fungal recognition and the modulation of the innate immune response.
InvivoGen offers an expanding collection of tools to study C-type Lectin Receptors, in particular Dectin-1: a macrophage derived Dectin-1 reporter cell line, various Dectin-1 ligands, Dectin-1 and Mincle antibodies, shRNAs as CLR inhibitors, and fully sequenced CLR and related genes.