CLR Ligands

Schematic representation of the Dectin-1 major isoformsDectin-1 & Mincle Agonists

Dectin-1 is a specific receptor of β-glucans, which are glucose polymers found in the cell walls of fungi, including the yeasts Saccharomyces cerevisiae and Candida albicans.
All Dectin-1 ligands are tested for Dectin-1 stimulation using Raw-Blue™ reporter cells.

Mincle is a multi-task danger receptor that recognizes a wide variety of ligands such as damaged cells, fungus, yeast and mycobacteria.

Dectin-1 Agonists

Beta-glucan peptide (BGP) Dectin-1 Agonist - Beta-glucan from Trametes versicolor 50 mg
Curdlan AL Dectin-1 Agonist - Beta-1,3-glucan from A. faecalis 1 g
HKCA Dectin-1 Agonist - Heat-killed C. albicans 10e9 cells
HKSC Dectin-1 Agonist - Heat-killed S. cerevisiae 10e9 cells
Laminarin Dectin-1 ligand -Soluble beta-glucan from Laminaria digitata 100 mg
Lichenan Dectin-1 Agonist - Beta-glucan from Cetriana islandica 100 mg
Pustulan Dectin-1 Agonist - Beta-D-glucan from lichen Lasallia pustulata 100 mg
Schizophyllan Dectin-1 Agonist - Beta-glucan from Schizophyllum commune 100 mg
Scleroglucan Dectin-1 Agonist - Beta-glucan from Sclerotium rolfsii 100 mg
WGP Dispersible Dectin-1 Agonist - Whole Glucan Particles, insoluble 50 mg
WGP Soluble WGP control / Dectin-1 inhibitor - Whole Glucan Particles, soluble 50 mg
Zymosan TLR2 Agonist - Dectin-1 Agonist - Cell wall preparation of S. cerevisiae 100 mg
Zymosan Depleted Dectin-1 Agonist - Hot alkali treated zymosan 10 mg

Dectin-2 Agonist

Furfurman Dectin-2 agonist - Malassezia furfur cell wall preparation 10 mg

Mincle Agonist

HKMT Mincle Agonist - TLR2 Agonist - Heat-killed Mycobacterium tuberculosis 10 mg
50 mg
TDB Mincle Agonist - Synthetic analog of the cord factor 2 x 1 mg
TDB VacciGrade™ Mincle agonist - Synthetic analog of the cord factor
Th1 response
2 mg
TDB-HS15 Mincle Agonist - Synthetic cord factor analog formulated with HS15 2 mg
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Note that the sequence of available ORFs provided by InvivoGen can differ from a given reference Genbank record due to genetic variations and/or alternative splicing. Customers should verify that the version of a gene sold by InvivoGen is suitable for the customer needs.
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