Reporter Detection Kits
Gene reporter systems are extensively used for the study of eukaryotic gene expression and regulation. Although they play a significant role in numerous applications, they most frequently serve as indicators of transcriptional activity in cells. The reporter gene of choice is combined to a promoter sequence and can be subsequently assayed in vitro or in vivo.
An ideal reporter gene is not endogenously expressed by the target cells creating background signals and can be detected through assays that are easy, sensitive and reliable.
InvivoGen provides two reporter gene systems that can be measured by histochemical staining of cells or tissues:
• β-Galactosidase (LacZ) reporter gene system
• Secreted embryonic alkaline phosphatase (SEAP) reporter gene system
Furthermore, InvivoGen has developed two specific media that allow fast and convenient detection of secreted alkaline phosphatase, called QUANTI-Blue™ and HEK-Blue™ Detection.
