Inflammasome Test Cells

Inflammasome Test Cells

THP-1 human monocytic cells are the most commonly used model cell line for studying inflammasome activation. They express high levels of NLRP3, ASC and pro-caspase-1.

InvivoGen provides engineered THP-1 cells that express reduced levels of NLRP3 or ASC and a new CASP-1 knockdown cell line.
All of these cell lines are useful for determining whether a signal activates the inflammasome, in particular the NLRP3 inflammasome.

Inflammasome Test Cells

THP1-defASC cells Human THP-1 Monocytes - ASC-deficient 3-7 x 10e6 cells
THP1-defCASP1 Cells NEW! Human THP-1 Monocytes - caspase-1 deficient 3-7 x 10e6 cells
THP1-defNLRP3 cells Human THP-1 Monocytes - NLRP3-deficient 3-7 x 10e6 cells
THP1-Null cells Human THP-1 Monocytes - Positive Control for Inflammasome Studies 3-7 x 10e6 cells
Disclaimer: Our products are provided for research purpose only. Commercial applications may require licensing from third parties.
Note that the sequence of available ORFs provided by InvivoGen can differ from a given reference Genbank record due to genetic variations and/or alternative splicing. Customers should verify that the version of a gene sold by InvivoGen is suitable for the customer needs.
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