IL-1β/IL-18 Sensor cells

InvivoGen has developed IL-1β and IL-18 reporter cells derived fom the human embryonic kidney HEK293 cell line.

HEK-Blue™ IL-1β, HEK-Blue™ IL-1R and HEK-Blue™ IL-18 cells are useful to monitor bioactive IL-1β and IL-18 released by test cells upon inflammasome activation.

These cell lines express a secreted alkaline phosphatase (SEAP) reporter gene which is induced by NF-κB/AP-1 upon activation of the cytokine signaling cascade. Levels of SEAP in the supernatant can be easily monitored using QUANTI-Blue™.

HEK-Blue™ IL-1β CellsHuman & Mouse IL-1β Sensor Cells3-7 x 10e6 cells
HEK-Blue™ IL-18 CellsHuman & Mouse IL-18 Sensor Cells3-7 x 10e6 cells
HEK-Blue™ IL-1R CellsHuman & Mouse IL-1 Sensor Cells3-7 x 10e6 cells
Disclaimer: Our products are provided for research purpose only. Commercial applications may require licensing from third parties.
Note that the sequence of available ORFs provided by InvivoGen can differ from a given reference Genbank record due to genetic variations and/or alternative splicing. Customers should verify that the version of a gene sold by InvivoGen is suitable for the customer needs.
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