Innate Immunity Signaling Inhibitors

InvivoGen offers a selection of known inhibitors of the signaling pathways initiated by pattern recognition receptors (PRRs). These inhibitory molecules intervene in the different steps of PRR activation and signaling cascade, including ligand binding and interaction with adapters.

Pathways of Inhibitors of Innate Immunity Signaling

2-AminopurinePKR Inhibitor250 mg
Ac-YVAD-cmkCaspase-1 inhibitor5 mg
AmlexanoxTBK1/IKKε inhibitor50 mg
Bafilomycin A1Endosomal Acidification Inhibitor - Autophagy Inhibitor10 µg
BX795TBK1/IKKε inhibitor - TLR signaling inhibitor - RLR Inhibitor5 mg
ChloroquineEndosomal Acidification Inhibitor - TLR signaling inhibitor - Autophagy Inhibitor250 mg
CLI-095TLR signaling inhibitor - TLR4 signaling inhibitor1 mg
Cyclosporin ACalcineurin inhibitor100 mg
CYT387JAK1/JAK2 & TBK1/IKK-ε inhibitor10 mg
GefitinibTLR signaling inhibitor - RIP2 tyrosine kinase inhibitor (Iressa)10 mg
GlybenclamideNLRP3 Inflammasome Inhibitor - Proton pump inhibitor1 g
H-89PKA inhibitor5 mg
IsoliquiritigeninNLRP3 inflammasome inhibitor10 mg
MCC950 NEWNLRP3-inflammasome inhibitor10 mg
OxPAPCTLR signaling inhibitor - TLR2 and TLR4 inhibitor1 mg
ParthenolideCaspase-1 and inflammasome inhibitor50 mg
Pepinh-MYDTLR signaling inhibitor - MyD88 inhibitory peptide2 mg
Pepinh-TRIFTLR signaling inhibitor - TRIF inhibitory peptide2 mg
PiceatannolCLR signaling inhibitor - Syk inhibitor5 mg
Polymyxin BTLR signaling inhibitor - LPS-induced TLR4 activation inhibitor100 mg
R406Syk inhibitor2 mg
RapamycinmTOR inhibitor - TLR signaling inhibitor - Autophagy Inducer5 mg
VX-765Caspase-1 inhibitor 10 mg
50 mg
YM201636PIKfyve Inhibitor5 mg
Z-VAD-FMKPan-caspase inhibitor - NLRP3 Inflammasome Inhibitor1 mg
Disclaimer: Our products are provided for research purpose only. Commercial applications may require licensing from third parties.
Note that the sequence of available ORFs provided by InvivoGen can differ from a given reference Genbank record due to genetic variations and/or alternative splicing. Customers should verify that the version of a gene sold by InvivoGen is suitable for the customer needs.
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