TLR9 Ligands

Toll-like receptor 9 (TLR9) recognizes specific unmethylated CpG oligonucleotide (ODN) sequences that distinguish microbial DNA from mammalian DNA. Three types of stimulatory ODNs have been described: type A, B and C.

InvivoGen provides a comprehensive collection of stimulatory or inhibitory CpG ODNs, their control ODNs, and labeled CpG ODNs. HEK-Blue™ TLR9 Cells are used to validate the functionality of these ligands. ODN 1826 VacciGrade™ and ODN 2006 VacciGrade™ (preclinical grade: sterile and endotoxin level <1 EU/mg) for use as a vaccine adjuvant are also available.

Disclaimer: Our products are provided for research purpose only. Commercial applications may require licensing from third parties.
Note that the sequence of available ORFs provided by InvivoGen can differ from a given reference Genbank record due to genetic variations and/or alternative splicing. Customers should verify that the version of a gene sold by InvivoGen is suitable for the customer needs.
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