CpG-free HSV1-tk::Sh

Suicide genes code for enzymes that convert non-toxic compounds (prodrugs) into toxic products.
The thymidine kinase (tk) gene from Herpes simplex virus type 1 (HSV1) codes for thymidine kinase, an enzyme able to convert nucleoside analogs such as ganciclovir into cytotoxic molecules.

InvivoGen has engineered a synthetic CpG-free fusion gene between the HSV1-tk gene and the Sh ble gene conferring Zeocin™ resistance. This fusion gene enables a better and faster selection of Zeocin-resistant clones. The CpG-free HSV1-tk::Sh fusion gene is provided in the expression plasmid pSelect-zeo which is selectable with Zeocin™ in both mammalian and E.coli cells.


Gene: CpG-free HSV1-tk::Sh
Description: Synthetic HSV1 thymidine kinase - Zeocin™ resistance fusion gene
Selection: Zeocin™

372 CpG in native gene


• 20 μg of pSELECT-zeo-HSV1-tk::Sh plasmid provided as lyophilized DNA
• 4 pouches of E. coli Fast-Media® Zeo (2 TB and 2 Agar)



Cat. Codepsetz-hsv1tksh
Unit Size20 µg
Price For price or distributor address,
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Note that the sequence of available ORFs provided by InvivoGen can differ from a given reference Genbank record due to genetic variations and/or alternative splicing. Customers should verify that the version of a gene sold by InvivoGen is suitable for the customer needs.
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