Fungin™
Prevention and Elimination of Fungi
Fungin™ is used as a "routine addition" to cell culture media to prevent yeast and fungal contaminations in small or large scale animal cell cultures. Fungin™ replaces Amphotericin B preparations.
Fungin™ is a new soluble form of Pimaricin, a polyene introduced in the 1950’s as an anti-fungal agent. This antimycotic compound kills yeasts, molds and fungi by disrupting ionic exchange through the cell membrane. Fungin™ is cell culture tested, and may be added to media containing commonly used antibacterial agents.
Specifications
Formula: C33H47NO13
Molecular weight: 665.74
Active concentration: from 10 μg/ml to 50 μg/ml
Highly stable and water soluble compound
Compatible with Pen / Strep solutions
No toxicity on treated cells and no deleterious effects on cell metabolism
Shipped at room temperature and still active after 6 days at 37°C
Documents
Contents
Fungin™ is provided as a pale yellow solution at a concentration of 10 mg/ml in different formats:
- 5 x 1.5 ml vial (75 mg)
- 1 x 20 ml vial ( 200 mg)
Description
Fungin™ is a new soluble formulation of Pimaricin, a polyene newly introduced to use in cell culture safety.
Fungin™ is a highly stable soluble compound, it does not need to be dissolved in toxic deoxycholate.
Fungin™ kills fungi and yeast by interfering with the cell membrane. The ergosterol, only found in fungi and yeast, is the primary site of action of Pimaricin. This polyene-induced distortion of selective membrane permeability results in a leakage of potassium and magnesium ions and a decrease of macromolecule synthesis. The death of fungi and yeast cells is characterized by the penetration of protons resulting in intracellular acidification.
ORDERING
Fungin™
| Cat. Code | ant-fn-1 |
|---|---|
| Unit Size | 75 mg (5 x 1.5 ml) |
| Price | For price or distributor address, please select your country |
Fungin™
| Cat. Code | ant-fn-2 |
|---|---|
| Unit Size | 200 mg (1 x 20 ml) |
| Price | For price or distributor address, please select your country |
