Cell Lines
InvivoGen offers a large panel of human and mouse cell lines
These cell lines are designed to:
- Study specific gene function(s)
- Investigate cell signaling pathways and signal transduction
- Screen for agonists/antagonists of pattern recognition receptors (PRRs), such as Toll-like receptors (TLRs), C-type lectin receptors (CLRs), cytosolic DNA sensors (CDSs), and aryl hydrocarbon receptor (AhR)
- Control the expression of cytotoxic genes
- Screen for toxic protein inhibitors
- Measure cytokine production
- Validate antibody functions
Various cell types
InvivoGen offers immortalized cell lines, isolated from various human or mouse tissues, that are widely used for in vitro biomedical research:
Expanding collection of reporter cell lines
Most of our cell lines express an NF-κB-inducible SEAP (secreted embryonic alkaline phosphatase) and/or IRF-inducible Lucia luciferase. Both reporter proteins are secreted and thus can be readily detected in the cell supernatant using the appropriate detection reagent.
Seven major families of reporter cells are available to meet your research needs:
- Transcription factor reporter cells (NF-κB, IRF, or NFAT pathways)
- PRR reporter cells (TLRs, CLRs, CDSs & STING, NLRs, RLRs, AhR, ALPK1/TIFA, inflammasomes)
- Cytokine reporter cells
- ADCC and ADCC cellular assays
- Immune checkpoint cellular assays
- Autophagy reporter cells
- COVID-19 reporter cells
InvivoGen’s cell lines are extensively tested for viability, stability, biological activity, and absence of mycoplasma to ensure strong and reproducible results. Moreover, we provide detailed handling and experimental procedures for all cell lines, to minimize the need for optimization or troubleshooting by the end-user.
Download our product flyer presenting InvivoGen’s Reporter Cell Lines.
ANY QUESTIONS ABOUT OUR CELL LINES?