The NOD2 agonist, MDP (muramyl dipeptide), is the minimal bioactive peptidoglycan motif common to all bacteria and the essential structure required for adjuvant activity in vaccines. The cell wall of mycobacteria is extremely immunogenic and this potent activity is attributed to their MDP which is N-glycolylated in contrast to the MDP of most bacteria which is N-acetylated. N-glycolyl-MDP displays strong NOD2-mediated activity and is considered a potent adjuvant.


Specificity: NOD2 agonist
Working Concentration:
100 ng  - 10 µg/ml
Solubility: 5 mg/ml in water
Molecular weight: 508.48


•  5 mg N-glycolyl-MDP
• 1.5 ml sterile endotoxin-free water

N-glycolyl-MDP is provided as a lyophilized powder and shipped at room temperature. Store at -20°C. Lyophilized product is stable for 1 year at -20°C. Upon resuspension, N-glycolyl-MDP should be aliquoted and stored at -20°C. Resuspended product is stable for 6 months at -20°C when properly stored. Avoid repeated freeze-thaw cycles.



Description N-glycolylated muramyldipeptide
Cat. Codetlrl-gmdp
Unit Size5 mg
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