pUNO1-hSTING Unit size Cat. code Docs Qty Price
pUNO1 bearing the human STING gene
20 µg
pUNO1-mSTING Unit size Cat. code Docs Qty Price
pUNO1 bearing the mouse STING gene
20 µg

Expression-ready ORF Clones

Human STING gene, "wild type"


STING is essential for the IFN response to microbial or self-DNA, and acts as a direct sensor of cyclic dinucleotides (CDNs).
CDNs are important messengers in bacteria, affecting numerous responses of the prokaryotic cell, but also in mammalian cells, acting as agonists of the innate immune response.

Several non-synonymous variants of STING have been described in the human population. The prevalent human STING isoform, which contains an arginine at position 232 (R232), is present in ~60% of the human population and therefore, is considered the wild-type [1,2]. The hSTING-WT isoform is preferentially activated by 2’5’linkage-containing cGAMP isomers [3].



Stimulator of interferon response cGAMP interactor 1.
Stimulator of interferon genes.
Transmembrane protein 173.



1. Jin L. et al., 2011. Identification and characterization of a loss-of-function human MPYS variant. Genes Immun. 12(4):263-9.
2. Yi G. et al., 2013. Single nucleotide polymorphisms of human STING can affect Innate immune response to cyclic dinucleotides. PLoS One 8(10):e77846.
3. Gao P. et al., 2013. Structure-function analysis of STING activation by c[G(2',5')pA(3',5')p] and targeting by antiviral DMXAA. Cell. 154(4):748-62.

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ORF size : 1140 bp

Subclone : BspEI - NheI


Genbank : NM_028261.1

ORF size : 1137 bp

Subclone : AgeI - NheI


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pUNO1 Contents

  • 20 µg of lyophilized DNA
  • 2 x 1 ml blasticidin at 10 mg/ml


room temperature Product is shipped at room temperature.

store Lyophilized DNA should be stored at -20°C. Upon receipt, store blasticidin at 4°C or -20°C.

stability Resuspended DNA should be stored at -20°C and is stable for up to 1 year.

Alert Blasticidin is a harmful compound. Refer to the safety data sheet for handling instructions.

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