CpG-free HSV1-tk::Sh

Synthetic cytotoxic / resistance fusion gene in expression plasmid

ABOUT

Synthetic cytotoxic / resistance fusion gene in expression plasmid

Suicide genes code for enzymes that convert non-toxic compounds (prodrugs) into toxic products.

The thymidine kinase (tk) gene from Herpes simplex virus type 1 (HSV1) codes for thymidine kinase, an enzyme able to convert nucleoside analogs such as ganciclovir into cytotoxic molecules.

InvivoGen has engineered a synthetic CpG-free fusion gene between the HSV1-tk gene and the Sh ble gene conferring Zeocin™ resistance.

This fusion gene enables a better and faster selection of Zeocin-resistant clones.

The CpG-free HSV1-tk::Sh fusion gene is provided in the expression plasmid pSelect-zeo which is selectable with Zeocin™ in both mammalian and E.coli cells.

All products are for research use only, and not for human or veterinary use.

ABOUT

Synthetic cytotoxic / resistance fusion gene in expression plasmid

Suicide genes code for enzymes that convert non-toxic compounds (prodrugs) into toxic products.

The thymidine kinase (tk) gene from Herpes simplex virus type 1 (HSV1) codes for thymidine kinase, an enzyme able to convert nucleoside analogs such as ganciclovir into cytotoxic molecules.

InvivoGen has engineered a synthetic CpG-free fusion gene between the HSV1-tk gene and the Sh ble gene conferring Zeocin™ resistance.

This fusion gene enables a better and faster selection of Zeocin-resistant clones.

The CpG-free HSV1-tk::Sh fusion gene is provided in the expression plasmid pSelect-zeo which is selectable with Zeocin™ in both mammalian and E.coli cells.

All products are for research use only, and not for human or veterinary use.

Specifications

Gene: CpG-free HSV1-tk::Sh

Description: Synthetic HSV1 thymidine kinase - Zeocin™ resistance fusion gene

Backbone: pSELECT-zeo

Selection: Zeocin™

372 CpG in native gene

CONTENTS

Contents

  • Product: 
    pSELECT-zeo-HSV1tkSh
  • Cat code: 
    psetz-hsv1tksh
  • Quantity: 
    20 µg
Includes:

1 ml of Zeocin™ (100 mg/ml)

Shipping & Storage

  • Shipping method:  Room temperature
  • Storage:

    • Upon receipt, store at -20°C.

    Caution:

    • Avoid repeated freeze-thaw cycles

DOCUMENTS

Documents

pSELECT-zeo-HSV1tkSh

Technical Data Sheet

Plasmid Sequence

Safety Data Sheet

Certificate of analysis

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