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CpG-free HSV1-tk::Sh

pSELECT-zeo-HSV1tkSh Unit size Cat. code Docs Qty Price
20 µg
psetz-hsv1tksh
+-
$433.00

Suicide genes code for enzymes that convert non-toxic compounds (prodrugs) into toxic products.
The thymidine kinase (tk) gene from Herpes simplex virus type 1 (HSV1) codes for thymidine kinase, an enzyme able to convert nucleoside analogs such as ganciclovir into cytotoxic molecules.

InvivoGen has engineered a synthetic CpG-free fusion gene between the HSV1-tk gene and the Sh ble gene conferring Zeocin™ resistance. This fusion gene enables a better and faster selection of Zeocin-resistant clones. The CpG-free HSV1-tk::Sh fusion gene is provided in the expression plasmid pSelect-zeo which is selectable with Zeocin™ in both mammalian and E.coli cells.

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Specifications

Gene: CpG-free HSV1-tk::Sh
Description: Synthetic HSV1 thymidine kinase - Zeocin™ resistance fusion gene
Backbone:
 pSELECT-zeo
Selection: Zeocin™

372 CpG in native gene

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Contents

• 20 μg of pSELECT-zeo-HSV1-tk::Sh plasmid provided as lyophilized DNA
• 4 pouches of E. coli Fast-Media® Zeo (2 TB and 2 Agar)

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