CpG-free HSV1-tk::Sh

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Synthetic HSV1 thymidine kinase - Zeocin™ resistance fusion gene

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20 µg


Synthetic cytotoxic / resistance fusion gene in expression plasmid

Suicide genes code for enzymes that convert non-toxic compounds (prodrugs) into toxic products.

The thymidine kinase (tk) gene from Herpes simplex virus type 1 (HSV1) codes for thymidine kinase, an enzyme able to convert nucleoside analogs such as ganciclovir into cytotoxic molecules.

InvivoGen has engineered a synthetic CpG-free fusion gene between the HSV1-tk gene and the Sh ble gene conferring Zeocin™ resistance.

This fusion gene enables a better and faster selection of Zeocin-resistant clones.

The CpG-free HSV1-tk::Sh fusion gene is provided in the expression plasmid pSelect-zeo which is selectable with Zeocin™ in both mammalian and E.coli cells.

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Gene: CpG-free HSV1-tk::Sh

Description: Synthetic HSV1 thymidine kinase - Zeocin™ resistance fusion gene

Backbone: pSELECT-zeo

Selection: Zeocin™

372 CpG in native gene

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  • 20 µg of lyophilized DNA
  • 1 ml of Zeocin™ (100 mg/ml)

room temperature Product is shipped at room temperature

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