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Synthetic herpes simplex virus 1 (HSV1) thymidine kinase (TK) gene
Synthetic cytotoxic viral TK gene in expression plasmid
Suicide genes code for enzymes, such as thymidine kinases (TKs), that convert non-toxic compounds (prodrugs) into toxic products.
Invivogen provides the thymidine kinase gene from Herpes simplex virus type 1 (HSV1) that codes for TKs, an enzyme able to convert nucleoside analogs such as ganciclovir (GCV) into cytotoxic molecules.
The DNA sequence of this viral gene was modified by humanizing the codon usage and eliminating all the CpGs.Back to the top
Gene: CpG-free HSV1-tk
Description: Synthetic herpes simplex virus 1 (HSV1) thymidine kinase (TK) gene
121 CpG in native geneBack to the top
- 20 µg of lyophilized DNA
- 1 ml of Zeocin™ (100 mg/ml)
Product is shipped at room temperatureBack to the top