ODN 2006 FITC
|ODN 2006 FITC||Unit size||Cat. code||Docs||Qty||Price|
Class B - FITC-labeled ODN 2006
FITC labeled CpG oligonucleotide - Human TLR9 ligand
CpG ODNs are synthetic oligonucleotides that contain unmethylated CpG dinucleotides in particular sequence contexts (CpG motifs).
These CpG motifs are present at a 20-fold greater frequency in bacterial DNA compared to mammalian DNA.
They have been shown to induce a coordinated set of immune responses based on the activation of immune cells primarily involved in the recognition of these molecules.
ODN 2006 FITC is a CpG ODN class B with a preference for human TLR9.
ODN 2006 FITC can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
Synonyms:ODN 7909, PF_3512676
Specificity: human TLR9 agonist
Working concentration: 1 - 5 μM
ODN 2006 sequence : 5’- tcgtcgttttgtcgttttgtcgtt -3’ (24 mer)
Note: Bases are phosphorothioate (nuclease resistant).
Spectral Properties of FITC
Excitation λ max: 495 nm
Emission λ max: 520 nm
- 50 μg (6.2 nmol) lyophilized ODN 2006 labeled with FITC at the 3’ terminus
- 1 ml sterile endotoxin-free water
FITC ODN 2006 is shipped at room temperature
Stored at -20°C. Protect from light. Resuspended product should be stored at -20°C and protected from light.
Product is stable for 6 months.
Avoid repeated cycles of freeze-thaw.Back to the top