Reporter Cell Lines
InvivoGen provides a large choice of reporter cell lines designed to provide a simple, rapid and reliable method to monitor the activation of intracellular signaling pathways induced by microbial molecules or cytokines.
These engineered cell lines stably express inducible SEAP and/or Lucia luciferase reporter gene. Exposure to a stimulus induces the pathway modulating reporter activity that can be readily assessed qualitatively and quantitatively.
Families of reporter cells
- Transcription factor reporter cells allow the study of the NF-κB and/or IRF pathways
- PRR Reporter cells comprise TLR reporter cells, NOD reporter cells, RLR reporter cells, CLR reporter cells, CDS reporter cells, STING reporter cells and inflammasome reporter cells
- Cytokine reporter cells include HEK-Blue™ cytokine reporter cells