Reporter Cell Lines
InvivoGen offers a large panel of cell lines engineered to provide simple, rapid, and reliable monitoring of innate immunity-specific signaling pathways.
Our cells stably express one or two reporter proteins, the secreted embryonic alkaline phosphatase (SEAP) and/or the Lucia luciferase.
Both systems offer the great advantage of being secreted outside the cell, allowing for multiple and non-destructive readings over time.
InvivoGen has developed easy-to-use detection reagents: HEK-Blue™ Detection and QUANTI-Blue™ Solution for SEAP monitoring using a spectrophotometer, and QUANTI-Luc™ 4 Lucia/Gaussia for Lucia and Gaussia luciferase monitoring with a luminometer.
InvivoGen’s expanding collection of reporter cells is of human or mouse, hematopoietic or non-hematopoietic origin.
Six major families of reporter cells are available to meet your research needs:
- PRR reporter cells (TLRs, CLRs, CDSs & STING, NLRs, RLRs, AhR, inflammasomes)
- Transcription factor reporter cells (NF-κB, IRF, or NFAT pathways)
- Cytokine reporter cells
- Autophagy reporter cells
- Knock-out reporter cells
- COVID-19 reporter cells
Download our product flyer presenting InvivoGen’s Reporter Cell Lines.