ODNs - TLR9 Antagonists
Toll-like receptor 9 (TLR9) recognizes specific unmethylated CpG oligonucleotides (ODN) sequences that distinguish microbial DNA from mammalian DNA.
Studies suggest the existence of DNA sequences that can neutralize the stimulatory effect of CpG ODNs.
InvivoGen provides a comprehensive collection of inhibitory CpG ODNs and their control ODNs.
The functionality of these TLR ligands are validated using HEK-Blue™ TLR9 Cells.