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MBL1

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pUNO1-mMBL1

pUNO1 bearing the mouse MBL1 gene

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20 µg

puno1-mmbl1
+-
$473
  • About
  • Specifications
  • pUNO1 Contents

Expression-ready ORF Clones

Alias : MDP-A

 

Mannose-binding lectin (protein A) 1.

 

Mannose-binding lectin (MBL), also called mannose-binding protein (MBP) is a member of the collectin family of proteins in which collagen structures are associated with carbohydrate-recognizing lectin domains [1]. MBL is a serum protein that binds a large variety of sugar moieties expressed by bacteria, viruses, protozoa and helminths through a pattern-recognition mode of detection [2]. MBL can mediate phagocytosis of microorganisms and induce inflammatory responses. MBL can also activate the complement system via MBL-associated serine proteases (MASPs). MBL is encoded by a single human gene, mbl2 (mbl1 is a pseudogene) and by two mouse genes, mbl1 and mbl2 [3].

1. Holmskov U. et al., 2003. Collections and ficolins: humoral lectins of the innate immune defense. Annu Rev Immunol. 21:547-78..
2. Jack DL. & Turner MW., 2003. Anti-microbial activities of mannose-binding lectin. Biochem Soc Trans. 31(Pt 4):753-7.
3. Sastry, R. et al., 1995. Characterization of murine mannose-binding protein genes Mbl1 and Mbl2 reveals features common to other collectin genes. Mamm. Genome 6: 103-110. 

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Specifications

Mouse MBL1 (pUNO1-mMBL1)

Genbank : NM_010775.2
ORF size : 720 bp
Subclone : AgeI - NheI

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pUNO1 Contents

  • 20 µg of lyophilized DNA
  • 2 x 1 ml blasticidin at 10 mg/ml

 

room temperature Product is shipped at room temperature.

store Lyophilized DNA should be stored at -20°C. Upon receipt, store blasticidin at 4°C or -20°C.

stability Resuspended DNA should be stored at -20°C and is stable for up to 1 year.

Alert Blasticidin is a harmful compound. Refer to the safety data sheet for handling instructions.

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