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CDS & STING Inhibitors

InvivoGen provides inhibitors of the cytosolic dsDNA Sensor (CDS) and STING signaling pathways. This family includes:

- Direct inhibitors of cGAS, STING, or AIM2 sensors

- Inhibitors targeting TBK1/IKKε, kinases signaling downstream CDS & STING

- Inhibitors of cGAS and STING trafficking 

 

These inhibitors are chemically synthesized and are characterized by UHPLC, NMR, and MS.

For each lot, the biological activity is validated and the absence of bacterial contamination (e.g. endotoxins) is verified using cell-based assays.

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