ODN 2395 FITC
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Cat.code:
tlrl-2395f
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ABOUT
FITC labeled CpG oligonucleotide - Human / Mouse TLR9 ligand
CpG ODNs are synthetic oligonucleotides that contain unmethylated CpG dinucleotides in particular sequence contexts (CpG motifs). These CpG motifs are present at a 20-fold greater frequency in bacterial DNA compared to mammalian DNA.
They have been shown to induce a coordinated set of immune responses based on the activation of immune cells primarily involved in the recognition of these molecules.
ODN 2395 FITC is a C-class CpG ODN specific for human / mouse TLR9. ODN 2395 FITC can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
All products are for research use only, and not for human or veterinary use.
SPECIFICATIONS
Specifications
TLR9
5’-tcgtcgttttcggcgc:gcgccg-3’ (22 mer). Note: Bases are phosphorothioate (nuclease resistant), palindrome is in bold.
1-5 μM for cellular assays
Negative (tested using EndotoxDetect™ assay)
Cellular assays
TLR9 activity has been tested using HEK-Blue™ TLR9 cells.
Spectral Properties of FITC:
- Excitation λ max: 495 nm
- Emission λ max: 520 nm
CONTENTS
Contents
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Product:ODN 2395 FITC
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Cat code:tlrl-2395f
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Quantity:50 µg
2 ml of sterile endotoxin-free water
ODN 2395 is labeled with FITC at the 3’ terminus.
Shipping & Storage
- Shipping method: Room temperature
- Upon receipt, store at -20 °C
- Avoid repeated freeze-thaw cycles
- Protect from light
Storage:
Caution:
DOCUMENTS
Documents
Technical Data Sheet
Safety Data Sheet
Certificate of analysis
Need a CoA ?
