Anti-hACE2-mIgG2b
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Cat.code:
mabg-hace2-3
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ABOUT
Anti-human ACE2 mouse monoclonal antibody
InvivoGen provides a mouse monoclonal antibody (mAb) featuring:
- a variable region that specifically targets the human ACE2 transmembrane protein, established as the SARS-CoV-2 receptor [1]
- the mouse IgG2b constant region
The Anti-hACE2-mIgG2b antibody was obtained following Swiss mice immunization with DNA encoding hACE2. It is produced in hybridoma cells and purified by affinity chromatography with protein A.
Application
- Monitoring cell surface expression of human ACE2 in primary cells or engineered cell lines by FACS (see Figure)
Quality control
- Isotype confirmed by ELISA
- Functionality validated by FACS using HEK-Bue™ hACE2-TMPRSS2 cells
Read our reviews discussing SARS-CoV-2.
References
1. Hoffmann M. et al., 2020. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell. 181:1-16.
All products are for internal research use only, and not for human or veterinary use.
SPECIFICATIONS
Specifications
Monitoring cell surface expression of human ACE2 in primary cells or engineered cell lines by FACS
Sodium phosphate buffer with glycine, saccharose, and stabilizing agents
Flow cytometry
Each lot is tested by flow cytometry.
CONTENTS
Contents
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Product:Anti-hACE2-mIgG2b
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Cat code:mabg-hace2-3
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Quantity:3 x 100 µg
Shipping & Storage
- Shipping method: Room temperature
- -20°C
- Avoid repeated freeze-thaw cycles
Storage:
Caution:
DOCUMENTS
Documents
Technical Data Sheet
Safety Data Sheet
Validation Data Sheet
Certificate of analysis
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