Anti-hACE2 mouse IgG2b

Anti-human ACE2 antibody - Mouse IgG2b isotype

ABOUT

Anti-human ACE2 mouse monoclonal antibody

InvivoGen provides a mouse monoclonal antibody (mAb) featuring: 

  • a variable region that specifically targets the human ACE2 transmembrane protein, established as the SARS-CoV-2 receptor [1]
  • the mouse IgG2b constant region

The Anti-hACE2-mIgG2b antibody was obtained following Swiss mice immunization with DNA encoding hACE2. It is produced in hybridoma cells and purified by affinity chromatography with protein A.

Application

  • Monitoring cell surface expression of human ACE2 in primary cells or engineered cell lines by FACS (see Figure)

Quality control

  • Isotype confirmed by ELISA
  • Functionality validated by FACS using HEK-Bue™ hACE2-TMPRSS2 cells

 

Learn more on SARS-CoV-2Read our reviews discussing SARS-CoV-2.

 

References

1. Hoffmann M. et al., 2020. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell. 181:1-16.

All products are for internal research use only, and not for human or veterinary use.

SPECIFICATIONS

Specifications

Applications

Monitoring cell surface expression of human ACE2 in primary cells or engineered cell lines by FACS

Isotype
mIgG2b
Clone
1D10
Source
Hybridoma
Purification
Protein A
Formulation buffer

Sodium phosphate buffer with glycine, saccharose, and stabilizing agents

Preservative
Azide-free
Reconstitution buffer
Sterile water
Tested applications

Flow cytometry

Quality control

Each lot is tested by flow cytometry.

CONTENTS

Contents

  • Product: 
    Anti-hACE2-mIgG2b
  • Cat code: 
    mabg-hace2-3
  • Quantity: 
    3 x 100 µg

Shipping & Storage

  • Shipping method:  Room temperature
  • Storage:

    • -20°C

    Caution:

    • Avoid repeated freeze-thaw cycles

DOCUMENTS

Documents

Anti-hACE2-mIgG2b

Technical Data Sheet

Safety Data Sheet

Validation Data Sheet

Certificate of analysis

Need a CoA ?

Citations

CUSTOMER SERVICE & TECHNICAL SUPPORT

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