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Anti-hIL-28b-IgG

Anti-hIL-28b-IgG Unit size Cat. code Docs Qty Price
Human IL-28b Neutralizing antibody - Monoclonal Mouse IgG1
3 x 100 µg
mabg-hil28b-3
+-
$258.00

Neutralizing monoclonal antibody against human interleukin 28b

Anti-hIL-28b-IgG is a monoclonal antibody specific for human interleukin 28B (hIL-28B).

This antibody has been selected for its ability to efficiently neutralize the biological activity of hIL-28B.

Anti-hIL-28b-IgG is produced in hybridomas and purified by affinity chromatography.

Figures

Evaluation of IFN-λ inhibition
Evaluation of IFN-λ inhibition

Neutralizing activity of IFN-λ antibodies: HEK-Blue™ IFN-α/β cells were incubated with 10 ng/ml recombinant hIL-28a, hIL28b, hIL-29 and increasing concentrations of their cognate antibody. After 24h incubation, recombinant IFN-λ induced ISG activation was assessed by measuring SEAP levels in the supernatant using QUANTI-Blue™. Percentages of maximal response (no antibody) and IC50 for 10 ng/ml of each cytokine is shown.

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Specifications

Applications (Other applications have not been tested) :
      B/N (block / neutralize)

Target: natural and recombinant human IL-28B

Specificity: No cross-reactivity with human IL-28A, mouse IL-28A or mouse IL-28B.

Clone: 18F4

Isotype: Mouse IgG1

Control: Mouse IgG1 Control

Immunogen: Human IL-28B protein expressed in Swiss mice following DNA immunization

Formulation: 0.2 µm filtered solution in Tris HCl buffer with saccharose, glycine and stabilizing agents

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Contents

  • 3 x 100 μg purified anti-hIL-28b-IgG antibody, provided azide-free and lyophilized

room temperature Product is shipped at room temperature.

store Store lyophilized antibody at -20 °C.

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