Anti-hIL-28b-IgG

Neutralizing monoclonal antibody against human interleukin 28b

Anti-hIL-28b-IgG is a monoclonal antibody specific for human interleukin 28B (hIL-28B).

This antibody has been selected for its ability to efficiently neutralize the biological activity of hIL-28B.

Anti-hIL-28b-IgG is produced in hybridomas and purified by affinity chromatography.

Figures

Neutralizing activity of IFN-λ antibodies: HEK-Blue™ IFN-α/β cells were incubated with 10 ng/ml recombinant hIL-28a, hIL28b, hIL-29 and increasing concentrations of their cognate antibody. After 24h incubation, recombinant IFN-λ induced ISG activation was assessed by measuring SEAP levels in the supernatant using QUANTI-Blue™. Percentages of maximal response (no antibody) and IC50 for 10 ng/ml of each cytokine is shown.

Specifications

Applications: B/N (block/neutralize)

Target: natural and recombinant human IL-28B

Specificity: No cross-reactivity with human IL-28A, mouse IL-28A or mouse IL-28B.

Clone: 18F4

Isotype: Mouse IgG1, kappa

Control: Mouse IgG1 Control

Immunogen: Human IL-28B protein expressed in Swiss mice following DNA immunization

Formulation: 0.2 µm filtered solution in Tris HCl buffer with saccharose, glycine and stabilizing agents

Contents

• 3 x 100 μg purified anti-hIL-28b-IgG antibody, provided azide-free and lyophilized

Product is shipped at room temperature.

Store lyophilized antibody at -20 °C.