Innate immunity / PRR / Inflammasome
NLRP3 is the best-described inflammasome sensor and an attractive drug target.
Innate immunity / PRR
The development of immune checkpoint inhibitors (ICIs) has revolutionized cancer immunotherapy...
Antibodies
Immune Checkpoint Anti-human Antibodies, ADCC Reporter Cell-Based Assay, Antibody Engineering
Innate immunity / PRR
The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcriptional factor widely expressed...
Antibodies / Vaccine & immunoglobulin
Antibodies are immunoglobulin (Ig) molecules made up of 2 large heavy chains (~55 kDa each) and 2...
STING / Innate immunity / PRR
STING (stimulator of interferon genes), alternatively known as MPYS, TMEM173, MITA and ERIS, is a...
Innate immunity / PRR
β-Glucans have been consumed for many centuries for their healing properties. Since the discovery of...
STING / Innate immunity / Vaccination
Adjuvants enhance and direct the adaptive immune response to vaccine antigens through various...
Innate immunity
The innate immune system is an evolutionarily conserved system acting as a first-line of defense...
Products
Luciferases encompass a wide range of enzymes used for bioluminescence, the emission of light...
STING / Innate immunity / PRR
The innate immune system provides the first line of defense against infectious pathogens and serves...
Innate immunity / PRR
The Third International DAMPs and Alarmins Symposium was held in Pittsburgh, USA in 2008. The aim of...
Products
The design of siRNAs and short hairpin siRNAs (shRNAs) remains an empirical process since the...
Innate immunity / PRR
Dectin-1 is a recently discovered pattern-recognition receptor that plays an important role in...
Innate immunity / PRR
Toll-like receptor 9 (TLR9) senses unmethylated CpG dinucleotides, a hallmark of microbial DNA, that...
Innate immunity / IFN responses
RNA interference (RNAi) has become a powerful tool to uncover gene function and is evolving as a new...
