Poly(I:C) (LMW) Rhodamine
|Poly(I:C) (LMW) Rhodamine||Unit size||Cat. code||Docs||Qty||Price|
Rhodamine-labeled TLR3 Agonist
Rhodamine-labeled poly(I:C) (LMW)
Poly(I:C) Rhodamine was chemically labeled by covalent coupling of a rhodamine probe containing a reactive alkylating group. This confers fluorescent properties to poly(I:C) (LMW) whilst retaining TLR3 recognition properties.
Polyinosinic-polycytidylic acid (poly(I:C)) is a synthetic analog of double stranded RNA (dsRNA), a molecular pattern associated with viral infection. Both natural and synthetic dsRNAs are known to induce type I interferons (IFN) and other cytokines production. Poly(I:C) is recognized by Toll-like receptor 3 (TLR3).
InvivoGen provides poly(I:C) with a high molecular weight (HMW) or a low molecular weight (LMW) that might activate the immune system differently.
Specificity: TLR3 agonist
Working Concentration: 100 ng - 10 μg/ml
Endotoxin level: EndoFit™ (<0.001 EU/μg)
Spectral Properties of Rhodamine
Excitation λ max: 546 nm
Emission λ max: 576 nm
• 10 µg Poly(I:C) Rhodamine
• 2 ml sterile endotoxin-free water
Poly(I:C) Rhodamine is shipped at room temperature and should be stored at -20°C.
Protect from light. Lyophilized product is stable 6 months at -20°C. Upon resuspension, Poly(I:C) Rhodamine should be aliquoted and stored at -20°C. Resuspended product is stable 3 months at -20°C. Avoid repeated freeze-thaw cycles.Back to the top