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Poly(I:C) (LMW) Rhodamine

Poly(I:C) (LMW) Rhodamine Unit size Cat. code Docs Qty Price
Rhodamine-labeled TLR3 Agonist
10 µg
tlrl-piwr
+-
$109.00

Rhodamine-labeled poly(I:C) (LMW)

Poly(I:C) Rhodamine was chemically labeled by covalent coupling of a rhodamine probe containing a reactive alkylating group. This confers fluorescent properties to poly(I:C) (LMW) whilst retaining TLR3 recognition properties.

Polyinosinic-polycytidylic acid (poly(I:C)) is a synthetic analog of double stranded RNA (dsRNA), a molecular pattern associated with viral infection.

Both natural and synthetic dsRNAs are known to induce type I interferons (IFN) and other cytokines production.

Poly(I:C) is recognized by Toll-like receptor 3 (TLR3).

InvivoGen provides poly(I:C) with a high molecular weight (HMW) or a low molecular weight (LMW) that might activate the immune system differently.

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Specifications

Specificity: TLR3 agonist

Working Concentration: 100 ng - 10 μg/ml

Spectral Properties of Rhodamine

  • Excitation λ max: 546 nm
  • Emission λ max: 576 nm
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Contents

  • 10 µg Poly(I:C) Rhodamine
  • 2 ml sterile endotoxin-free water

room temperature Poly(I:C) Rhodamine is shipped at room temperature

store Stored at -20°C.

Alert Protect from light.

Lyophilized product is stable 6 months at -20°C. Upon resuspension, Poly(I:C) Rhodamine should be aliquoted and stored at -20°C. 

Resuspended product is stable 3 months at -20°C.

Avoid repeated freeze-thaw cycles.

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