ODN 2216 Biotin - TLR9 Agonist

Biotin-labeled CpG ODN 2216, Class A, Human-preferred

ABOUT

Biotin labeled CpG oligonucleotide - Human TLR9 ligand

CpG  ODNs are synthetic oligonucleotides that contain unmethylated CpG  dinucleotides in particular sequence contexts (CpG motifs).

These CpG  motifs are present at a 20-fold greater frequency in bacterial DNA  compared to mammalian DNA. They have been shown to induce a coordinated  set of immune responses based on the activation of immune cells  primarily involved in the recognition of these molecules.

ODN 2216 Biotin is a A-class CpG ODN with a preference for human TLR9.

ODN 2216 Biotin can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.

All products are for internal research use only, and not for human or veterinary use.

SPECIFICATIONS

Specifications

Working concentration

1-5 μM

Tested applications

Cellular assays

Applications

Evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.

Quality control

Each lot is functionally tested and validated.

CONTENTS

Contents

  • Product: 
    ODN 2216 Biotin
  • Cat code: 
    tlrl-2216b
  • Quantity: 
    2 x 50 µg
Includes:

1.5 ml endotoxin-free water

Notes:

ODN 2216 labeled with Biotin at the 3’ terminus

Shipping & Storage

  • Shipping method:  Room temperature

    • Storage:

    • -20°C

    Caution:

    • Avoid repeated freeze-thaw cycles

DOCUMENTS

Documents

ODN 2216 Biotin

Technical Data Sheet

Safety Data Sheet

Certificate of analysis

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