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Plasmocure™ - Mycoplasma Elimination Reagent

Plasmocure™ Unit size Cat. code Docs Qty Price
Antimycoplasma agent
100 mg (1 ml)
ant-pc
+-
$248.00

You may also need : PlasmoTest™ - Mycoplasma Detection Kit | View more associated products

Antimicrobial agent | Plasmocure™ | InvivoGen

Alternative mycoplasma removal agent

Plasmocure™ is recommended for the eradication of mycoplasmas that appear, in very rare cases, to be resistant to Plasmocin™.

Plasmocure™ is active against various mycoplasma species that infect mammalian cell cultures including M. hyorhinis, M. orale, M. arginini, M. fermentans, M. hominis and Acholeplasma laidlawii.

Plasmocure™ combines two antibiotics that act through different mechanisms than those found in Plasmocin™.

  • The first antibiotic binds to the 50S subunit of the ribosome and blocks peptidyltransferase activity.
  • The second anticbiotic binds to isoleucyl-tRNA synthetase and halts the incorporation of isoleucine into bacterial proetins.

A two-week treatment with Plasmocure™ is usually sufficient to completely eliminate the mycoplasmas.

A moderate toxicity can be observed during the course of the treatment but full recovery of the cell line is expected once mycoplasmas are eliminated.

 

 Read our review on Mycoplasma contamination of cell cultures

 Read our review on Mycoplasma eradication

 

InvivoGen's anti-mycoplasma products are suitable for research purposes only, and not for human or animal care.

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Specifications

Product concentration: 100 mg/ml

Elimination of mycoplasmas in two weeks (recommended concentration of 50 μg/ml)

​Endotoxin level: < 0.5 EU/mg

Physicochemical characterization: pH and appearance

Cell culture tested: potency validated on bacterial reference strains

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Contents

Plasmocure™ is provided as a cell culture tested, sterile filtered solution at a concentration of 100 mg/ml.

Plasmocure™ is shipped a t room temperature

Upon receipt it can be stored at 4°C for 12 months or at -20°C for long-term storage.

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Citations

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