Plasmocure™ - Mycoplasma Elimination Reagent
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100 mg (1 ml)
Alternative mycoplasma removal agent
Plasmocure™ is recommended for the eradication of mycoplasmas that appear, in very rare cases, to be resistant to Plasmocin™.
Plasmocure™ is active against various mycoplasma species that infect mammalian cell cultures including M. hyorhinis, M. orale, M. arginini, M. fermentans, M. hominis and Acholeplasma laidlawii.
Plasmocure™ combines two antibiotics that act through different mechanisms than those found in Plasmocin™.
- The first antibiotic binds to the 50S subunit of the ribosome and blocks peptidyltransferase activity.
- The second anticbiotic binds to isoleucyl-tRNA synthetase and halts the incorporation of isoleucine into bacterial proetins.
A two-week treatment with Plasmocure™ is usually sufficient to completely eliminate the mycoplasmas.
A moderate toxicity can be observed during the course of the treatment but full recovery of the cell line is expected once mycoplasmas are eliminated.
Read our review on Mycoplasma contamination of cell cultures
Read our review on Mycoplasma eradication
InvivoGen's anti-mycoplasma products are suitable for research purposes only, and not for human or animal care.Back to the top
Product concentration: 100 mg/ml
Elimination of mycoplasmas in two weeks (recommended concentration of 50 μg/ml)
Endotoxin level: < 0.5 EU/mg
Physicochemical characterization: pH and appearance
Cell culture tested: potency validated on bacterial reference strainsBack to the top
Plasmocure™ is provided as a cell culture tested, sterile filtered solution at a concentration of 100 mg/ml.
Plasmocure™ is shipped a t room temperature
Upon receipt it can be stored at 4°C for 12 months or at -20°C for long-term storage.Back to the top