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Anti-hTNF-α-hIgA2

Anti-hTNF-α-hIgA2 Unit size Cat. code Docs Qty Price
Human TNF-α (adalimumab) antibody - Human IgA2
100 µg
htnfa-mab7
+-
$315.00

Neutralizing human IgA2 monoclonal antibody against human TNF-α

Anti-hTNF-α-hIgA2 is a neutralizing monoclonal antibody featuring the constant region of the human IgA2 isotype and the variable region of adalimumab.

Adalimumab is a fully human monoclonal antibody against the pro-inflammatory cytokine human tumor necrosis factor alpha (hTNF-α).

Adalimumab binds to TNF-α and blocks its interaction with TNF receptors thereby downregulating the inflammatory reactions associated with autoimmune diseases, such as rheumatoid arthritis and Crohn’s disease.

Anti-hTNF-α-hIgA2 was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography with peptide M.

The neutralizing activity of this human IgA2 antibody was determined using HEK-Blue™ TNF-α/IL-1β cells.

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Specifications

Clonality: Monoclonal antibody

Application: Neutralization of human TNF-α-induced cellular activation

Specificity: Human TNF-α

Isotype: Human IgA2

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Contents

  • 100 µg purified anti-hTNFα-hIgA2 antibody, provided azide-free and lyophilized

room temperature Product is shipped at room temperature.

store Store lyophilized antibody at -20°C.

stability Lyophilized product is stable for 1 year when properly stored.

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