Murine IgG2a Isotype Control

Monoclonal mouse IgG2a antibody against E. coli β-galactosidase for in vivo use

Anti-β-Gal-mIgG2a InvivoFit™ is a recombinant monoclonal antibody (mAb) comprising the variable region of the hybridoma-derived mAb Mouse IgG2a Control (clone: T9C6) that targets E. coli β-galactosidase (β-Gal). 

This mAb does not react with murine proteins. 

Anti-β-Gal-mIgG2a InvivoFit™ features the murine IgG2a isotype, a major immunoglobin present in serum. This isotype displays very high ADCP, high ADCC and high CDC [1].

This mAb is provided as an isotype control for use with InvivoGen's IgG2a antibodies in the mouse anti-mouse mAbs collection. 

It has been produced in CHO cells and purified by affinity chromatography with protein G.

Anti-β-Gal-mIgG2a InvivoFit™ is specifically adapted for in vivo use in mice:

• Sequence is 100% murine
• Guaranteed sterile, endotoxin level < 1 EU/mg
• Suitable for parenteral delivery in mice (azide-free)
• Low aggregation < 5%
• Produced in both animal-free facilities and defined media

Bulk quantities are available - contact us

References:

1. Nimmerjahn F. et al., 2005. FcgammaRIV: a novel FcR with distinct IgG subclass specificity. Immunity. 2005 Jul;23(1):41-51.

Specifications

Clonality: Monoclonal antibody

Specificity: E. coli β-galactosidase (β-Gal)

Isotype: Mouse IgG2a, kappa

Source: CHO cells

Purity: Purified by affinity chromatography with protein G

Quality control:

• Absence of binding confirmed by flow cytometry
• The complete sequence of this antibody has been verified
• < 5% aggregates (confirmed by size exclusion chromatography)
• Guaranteed sterile and <1 EU/mg (determined by the LAL assay)

Contents

• 1 mg purified anti-β-Gal-mIgG2a antibody, provided azide-free and lyophilized

Product is shipped at room temperature.

Store lyophilized antibody at -20 °C.

Lyophilized product is stable for at least 1 year.