InvivoGen provides monoclonal antibodies targeting human and murine IL-16 for detection and neutralization.
Interleukin-16 (IL-16) is a pro-inflammatory cytokine playing an important role in modulating T-cell activation, chemotaxis, and proliferation. It is also known for its ability to inhibit HIV replication. IL-16 is associated with the development of several cancers as well as inflammatory diseases such as polyarthritis, asthma, and lupus. Recent studies have put the spotlight on this pleiotropic cytokine by correlating its high plasmatic levels with COVID-19 severity.