|Anti-hCD20-mIgG2a||Unit size||Cat. code||Docs||Qty||Price|
Monoclonal mouse IgG2a antibody against human CD20
Anti-hCD20-mIgG2a features the constant region of the mouse IgG2a isotype and the variable region of rituximab. Rituximab is a mouse/human chimeric monoclonal antibody that targets the CD20 antigen found on the surface of malignant and normal B lymphocytes. Binding of rituximab to CD20 results in cell destruction through different mechanisms including direct signaling of apoptosis, complement activation and cell-mediated cytotoxicity. Rituximab has been approved by the FDA for the treatment of various lymphoid malignancies, including B-cell non-Hodgkin's lymphoma and B-cell chronic lymphocytic leukaemia.
Anti-hCD20-mIgG2a was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography with protein G.
Clonality: Monoclonal antibody
Specificity: Targets cells expressing human CD20
Isotype: Mouse IgG2a
100 µg purified anti-hCD20-mIgG2a antibody, provided azide-free and lyophilizedBack to the top