Our screening service offers a variety of PRR assays, ensuring tailored solutions for each research goal. Choose from human and mouse PRRs, with options that span critical immune pathways:

	Standard Panel Cell Lines	Positive Control Ligands	Pathway / Reporter
TLR Ligand Screening - Human or mouse -	HEK-Blue™ TLR2 HEK-Blue™ TLR3 HEK-Blue™ TLR4 HEK-Blue™ TLR5 HEK-Blue™ TLR7 HEK-Blue™ TLR8 HEK-Blue™ TLR9 HEK-Blue™ Null control	Pam3CSK4 Poly (I:C) HMW LPS EB Flagellin ST CL307 TL8-506 CpG ODN 2006 (ODN 1826 for mouse) Human TNF-α	NF-κB / SEAP (NF-κB / SEAP and IRF / Lucia Dual™ Readout available)
Specific TLR2 Ligand Screening - Human -	HEK-Blue™ TLR2 HEK-Blue™ TLR2-TLR1 HEK-Blue™ TLR2-TLR6 HEK-Blue™ TLR2 KO-TLR2/6 HEK-Blue™ Null control	CUT-12-9 CUT-12-9 FSL-1 Human TNF-α Human TNF-α	NF-κB / SEAP
NOD Ligand Screening - Human or mouse -	HEK-Blue™ NOD1 HEK-Blue™ NOD2 HEK-Blue™ Null control	C12-iE-DAP L18-MDP Human TNF-α	NF-κB / SEAP
CLR Ligand Screening - Human or mouse -	HEK-Blue™ Dectin1a HEK-Blue™ Dectin1b HEK-Blue™ Dectin2 (optional) HEK-Blue™ Mincle HEK-Blue™ Null control	WGPS / Zymosan Depleted WGPS / Zymosan Depleted HKCA TDB Human TNF-α	NF-κB / SEAP
STING Ligand Screening - Human or mouse -	THP1-Dual™ KO-STING THP1-Dual™ KI-STING variants THP1-Dual™ control	Human IFN-α / 2'3'-cGAMP Dependent on the STING variant Human IFN-α / 2'3'-cGAMP	NF-κB / SEAP and IRF / Lucia
RIG-I & MDA5 Ligand Screening - Human -	HEK-Dual™ RNA-hRIG-I HEK-Dual™ RNA-hMDA5 HEK-Dual™ RNA-Null control HEK-Lucia™ RIG-I HEK-Lucia™ Null control THP1-Dual™ KO-RIG-I THP1-Dual™ control A549-Dual™ KO-RIG-I A549-Dual™ control	Human IFN-α / 3p-hpRNA (complexed) Human IFN-α / Poly(I:C) (complexed) Human IFN-α / 3p-hpRNA / Poly(I:C) (complexed) Human IFN-α / 3p-hpRNA (complexed) Human IFN-α / 3p-hpRNA (complexed) Human IFN-α / 3p-hpRNA (complexed) Human IFN-α / 3p-hpRNA (complexed) Human IFN-α / 3p-hpRNA (complexed) Human IFN-α / 3p-hpRNA (complexed)	NF-κB / SEAP and IRF / Lucia IRF / Lucia NF-κB / SEAP and IRF / Lucia NF-κB / SEAP and IRF / Lucia

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