RNA interference (RNAi) is one of the most exciting discoveries of the past decade in functional genomics. RNAi is rapidly becoming an important method for analyzing gene functions in eukaryotes and holds promise for the development of therapeutic gene silencing. RNAi is a post-transcriptional process triggered by the introduction of short double-stranded RNA (siRNA, shRNA) which leads to gene silencing in a sequence-specific manner.
InvivoGen provides a set of cutting-edge tools to knockdown efficiently the expression of mammalian genes. These tools include the siRNA wizard software, shRNA cloning vectors and vectors expressing validated shRNAs, and systems for the prevalidation of siRNA/shRNAs or the detection of interferon response.