Jurkat Cells

Jurkat cells are a  human  immortalized T  lymphocyte  cell  line  derived  from  an  acute  T  cell  leukemia. Jurkat cells are used to study T cell signaling and the expression of various chemokine receptors susceptible to viral entry, particularly HIV. They are also widely used for the screening of the anticancer capability and mechanism of drugs.

Activation of Jurkat cells by phorbol 12-myristate 13-acetate (PMA) plus ionomycin results in the production of large amounts of interleukin-2 (IL-2).

InvivoGen provides Jurkat cells stably transfected with one or two reporter constructs designed for the study of the NFAT (nuclear factor of activated T-cells), NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) or IRF (interferon regulatory factor) pathways.

Jurkat-Dual™ cellsHuman T lymphocytes - NF-kB/IRF reporter cells3-7 x 10e6 cells
Jurkat-Lucia™ NFAT Cells NEWNFAT-Luc Reporter T lymphocytes3-7 x 10e6 cells
Disclaimer: Our products are provided for research purpose only. Commercial applications may require licensing from third parties.
Note that the sequence of available ORFs provided by InvivoGen can differ from a given reference Genbank record due to genetic variations and/or alternative splicing. Customers should verify that the version of a gene sold by InvivoGen is suitable for the customer needs.
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