Reporter Cell Lines
InvivoGen provides a large choice of reporter cell lines designed to provide a simple, rapid and reliable method to monitor the activation of intracellular signaling pathways induced by microbial molecules or cytokines.
These engineered cell lines stably express inducible SEAP and/or Lucia™ reporter gene. Exposure to a stimulus induces the pathway modulating reporter activity that can be readily assessed qualitatively and quantitatively.
Both reporter proteins are readily measurable in the cell culture supernatant when using HEK-Blue™ Detection or QUANTI-Blue™, SEAP detection reagents, or QUANTI-Luc™, a Lucia™ detection reagent.
Reporter Cell Lines
| B16 melanoma | Murine B16 melanoma - PRR and cytokine reporter cells |
|---|---|
| HEK 293 | Engineered human embryonic kidney (HEK) 293 cells - PRR or cytokine reporter |
| Jurkat T lymphocytes | Human T lymphocytes - PRR reporter cells |
| MEF | Murine embryonic fibroblasts from C3H or C57BL/6 - PRR reporter |
| Ramos B lymphocytes | Human B lymphocytes - PRR reporter cells |
| RAW 264.7 macrophages | Murine RAW 264.7 macrophages - PRR or cytokine reporter cells |
| THP-1 monocytes | Human THP-1 monocytes - PRR reporter cells |