OVA peptides

InvivoGen provides two standard OVA peptides for detection use (ELISPOT):

OVA 257-264 is a class I (Kb)-restricted peptide epitope of ovalbumin (OVA), presented by the class I major histocompatibility complex (MHC) molecule, H-2Kb [1]. It has been demonstrated that OVA 257-264 peptides can be used to detect a strong CD8+ cytolytic T cell response [2].

OVA 323-339 encompasses an allergenic and antigenic epitope of the ovalbumin protein [3]. OVA 323-339 peptide binds to I-A(d) MHC class II protein [4]. OVA 323-339 has been used extensively to study the nature of class II MHC-peptide binding and T-cell activation [5-6].


OVA 257-264
Description: H-2Kb-restricted OVA MHC class I epitope
MW: 963.2
Solubility:  2 mg/ml in water

OVA 323-339
Description: I-Ad-restricted OVA MHC class II epitope
MW: 1773.9
2 mg/ml in water


1 mg OVA 257-264 or OVA 323-339 provided lyophilized


1. Rötzschke O. et al., 1991. Exact prediction of a natural T cell epitope. Eur J Immunol.21(11):2891-4.
2. Lipford GB. et al., 1993. Primary in vivo responses to ovalbumin. Probing the predictive value of the Kb binding motif. J Immunol. 150(4):1212-1222.
3. McFarland BJ et al. 1999. Ovalbumin(323-339) peptide binds to the major histocompatibility complex class II I-A(d) protein using two functionally distinct registers. Biochemistry. 38(50):16663-70.
4. Johnsen G & Elsayed S. 1990. Antigenic and allergenic determinants of ovalbumin-111. MHC Ia-binding peptide (OA 323-339) interacts with human and rabbit specific antibodies. Mol Immunol. 27821-7.
5. Bickert T. et al. 2007. Murine polyomavirus-like particles induce maturation of bone marrow derived dendritic cells and proliferation of T cells. Med Microbiol Immunol 196:31–9.
6. Szymczak-Workman AL.et al. 2009. Cutting edge: regulatory T cells do not require stimulation through their TCR to suppress. J Immunol 1:182.


Recent articles using InvivoGen OVA peptides


OVA 257-264

Cat. Code vac-sin
Unit Size 1 mg
Price For price or distributor address,
please select your country

OVA 323-339

Cat. Code vac-isq
Unit Size 1 mg
Price For price or distributor address,
please select your country
Disclaimer: Our products are provided for research purposes only. Not for use in humans. Commercial applications may require licensing from third parties.
Note that the sequence of available ORFs provided by InvivoGen can differ from a given reference Genbank record due to genetic variations and/or alternative splicing. Customers should verify that the version of a gene sold by InvivoGen is suitable for the customer needs.
Copyrights © 2011-2016 InvivoGen. All Rights Reserved. Reproduction of any materials from this site is strictly forbidden without permission for commercial use. Nonprofit use for non-commercial research and educational purposes is permitted, citation should include the URL "www.invivogen.com".