ODN 2395

Class C CpG oligonucleotide - Human / Murine TLR9 ligand

CpG ODNs are synthetic oligonucleotides that contain unmethylated CpG dinucleotides in particular sequence contexts (CpG motifs). These CpG motifs are present at a 20-fold greater frequency in bacterial DNA compared to mammalian DNA. CpG ODNs are recognized by Toll-like receptor 9 (TLR9) leading to strong immunostimulatory effects.

ODN 2395 is a CpG ODN class C specific for human / mouse TLR9. C-class CpG ODNs contain a complete phosphorothioate backbone and a CpG-containing palindromic motif. C-class CpG ODNs induce strong IFN-α production from pDC and B cell stimulation.

ODN 2395TLR9 Agonist - Stimulatory CpG ODN, Class C, Human / mouse 200 µg
1 mg
5 mg
Bulk quantity
ODN 2395 controlNegative control for ODN 2395 200 µg
1 mg
5 mg
ODN 2395 FITCTLR9 Agonist - FITC-labelled CpG ODN 2395, Class C, Human / mouse50 µg
ODN 2395 VacciGrade™TLR9 agonist - CpG ODN, class C (human/mouse)
Th1 response
1 mg
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