Ubiquitous Promoters

Ubiquitous Promoters are strongly active in a wide range of cells, tissues and cell cycles.

Ubiquitous Promoters are available as native or composite promoter:
Native promoters, also called minimal promoters,  consist of a single fragment from the 5’ region of a given gene. Each of  them comprises a core promoter and its natural 5’UTR. In some cases,  the 5’UTR contains an intron.
Composite promoters combine promoter elements of different origins (e.g. SV40 enhancer/AFP  promoter) or were generated by assembling a distal enhancer with a  minimal promoter of the same origin (e.g. CEA enhancer/promoter).

In each pDRIVE, the promoter drives the expression of a reporter gene to  facilitate the evaluation of its activity. Three different reporter genes  are available in two different backbones: LacZ reporter gene in pDRIVE, secreted embryonic alkaline phosphatase (SEAP) or Lucia secreted luciferase reporter gene in pDRIVE5.

Native promoters

pDRIVE-β-Actβ-Act promoter (Ubiquitous) in pDRIVE expresssion plasmid Human - LacZ (20 µg)
Human - SEAP (20 µg)
Human - Lucia (20 µg)
pDRIVE-EF1EF1 promoter (Ubiquitous) in pDRIVE expresssion plasmid Mouse - LacZ (20 µg)
Rat - LacZ (20 µg)
Chimpanzee - LacZ (20 µg)
Mouse - SEAP (20 µg)
Rat - SEAP (20 µg)
Chimpanzee - SEAP (20 µg)
Mouse - Lucia (20 µg)
Rat - Lucia (20 µg)
Chimpanzee - Lucia (20 µg)
pDRIVE-EGR1EGR1 promoter (Ubiquitous, radiation inducible) in pDRIVE expresssion plasmid Human - LacZ (20 µg)
Human - SEAP (20 µg)
Human - Lucia (20 µg)
pDRIVE-eIF4A1eIF4A1 promoter (Ubiquitous) in pDRIVE expresssion plasmid Human - LacZ (20 µg)
Mouse - LacZ (20 µg)
Human - SEAP (20 µg)
Mouse - SEAP (20 µg)
Human - Lucia (20 µg)
Mouse - Lucia (20 µg)
pDRIVE-FerHFerH promoter (Ubiquitous) in pDRIVE expresssion plasmid Human - LacZ (20 µg)
Human - SEAP (20 µg)
Human - Lucia (20 µg)
pDRIVE-FerLFerL promoter (Ubiquitous) in pDRIVE expresssion plasmid Human - LacZ (20 µg)
Human - SEAP (20 µg)
Human - Lucia (20 µg)
pDRIVE-GAPDHGAPDH promoter (Ubiquitous) in pDRIVE expresssion plasmid Human - LacZ (20 µg)
Human - SEAP (20 µg)
Human - Lucia (20 µg)
pDRIVE-GRP78GRP78 promoter (Ubiquitous, stress inducible) in pDRIVE expresssion plasmid Mouse - Lucia (20 µg)
Human - LacZ (20 µg)
Human - SEAP (20 µg)
Mouse - LacZ (20 µg)
Human - Lucia (20 µg)
Mouse - SEAP (20 µg)
Rat - LacZ (20 µg)
Rat - SEAP (20 µg)
Rat - Lucia (20 µg)
pDRIVE-GRP94GRP94 promoter (Ubiquitous, stress inducible) in pDRIVE expresssion plasmid Rat - LacZ (20 µg)
Human - LacZ (20 µg)
Human - SEAP (20 µg)
Mouse - LacZ (20 µg)
Human - Lucia (20 µg)
Mouse - SEAP (20 µg)
Mouse - Lucia (20 µg)
Rat - SEAP (20 µg)
Rat - Lucia (20 µg)
pDRIVE-HSP70HSP70 promoter (Ubiquitous, heat inducible) in pDRIVE expresssion plasmid Human - LacZ (20 µg)
Human - SEAP (20 µg)
Human - Lucia (20 µg)
Mouse - LacZ (20 µg)
Mouse - SEAP (20 µg)
Mouse - Lucia (20 µg)
pDRIVE-β-Kinβ-Kin promoter (Ubiquitous) in pDRIVE expresssion plasmid Human - LacZ (20 µg)
Human - SEAP (20 µg)
Human - Lucia (20 µg)
pDRIVE-PGK-1PGK-1 promoter (Ubiquitous) in pDRIVE expresssion plasmid Mouse - LacZ (20 µg)
Mouse - SEAP (20 µg)
Mouse - Lucia (20 µg)
pDRIVE-ROSAROSA promoter (Ubiquitous) in pDRIVE expresssion plasmid Human - LacZ (20 µg)
Human - SEAP (20 µg)
Mouse - LacZ (20 µg)
Human - Lucia (20 µg)
Mouse - SEAP (20 µg)
Mouse - Lucia (20 µg)
pDRIVE-Ubiquitin BUbiquitin B promoter (Ubiquitous) in pDRIVE expresssion plasmid Human - Lucia (20 µg)
Human - LacZ (20 µg)
Human - SEAP (20 µg)

Composite promoters

pDRIVE-βAct / RU5'βAct / RU5' promoter (Ubiquitous) in pDRIVE expresssion plasmid Human - LacZ (20 µg)
Human - SEAP (20 µg)
Human - Lucia (20 µg)
pDRIVE-EF1 / RU5′EF1 / RU5′ promoter (Ubiquitous) in pDRIVE expresssion plasmid Rat - LacZ (20 µg)
Chimpanzee - LacZ (20 µg)
Rat - SEAP (20 µg)
Chimpanzee SEAP (20 µg)
Rat - Lucia (20 µg)
Chimpanzee Lucia (20 µg)
pDRIVE-SV40 / hFerH / mEF1SV40 / hFerH / mEF1 promoter (Ubiquitous) in pDRIVE expresssion plasmid Human - LacZ (20 µg)
Human - SEAP (20 µg)
Human - Lucia (20 µg)
pDRIVE-FerH / RU5′FerH / RU5′ promoter (Ubiquitous) in pDRIVE expresssion plasmid Human - LacZ (20 µg)
Human - SEAP (20 µg)
Human - Lucia (20 µg)
pDRIVE-CMV / FerL / chEF1CMV / FerL / chEF1 promoter (Ubiquitous) in pDRIVE expresssion plasmid Human - LacZ (20 µg)
Human - SEAP (20 µg)
Human - Lucia (20 µg)
pDRIVE-FerL / RU5′FerL / RU5′ promoter (Ubiquitous) in pDRIVE expresssion plasmid Human - LacZ (20 µg)
Human - SEAP (20 µg)
Human - Lucia (20 µg)
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