Monoclonal human IgE antibody against human CD20

Anti-hCD20-hIgE features the constant region of the human IgE isotype and the variable region of rituximab. Rituximab is a mouse/human chimeric monoclonal antibody that targets the CD20 antigen found on the surface of malignant and normal B lymphocytes. Binding of rituximab to CD20 results in cell destruction through different mechanisms including direct signaling of apoptosis, complement activation and cell-mediated cytotoxicity. Rituximab has been approved by the FDA for the treatment of various lymphoid malignancies, including B-cell non-Hodgkin's lymphoma and B-cell chronic lymphocytic leukaemia. Anti-hCD20-hIgE was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography withprotein L.


Clonality: Monoclonal antibody
Specificity: Targets cells expressing human CD20
Isotype: Human IgE


100 µg purified anti-hCD20-hIgE antibody, provided azide-free and lyophilized


Recent articles using InvivoGen Anti-hCD20-hIgE



Cat. Codehcd20-mab8
Unit Size100 µg
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