Poly(dA:dT) / LyoVec™
|Poly(dA:dT) / LyoVec™||Unit size||Cat. code||Docs||Qty||Price|
dsDNA naked - complexed with transfection reagent
Synthetic analog of B-DNA complexed with transfection reagent
Poly(dA:dT) is a poly(deoxyadenylic-deoxythymidylic) acid sodium salt. It is a repetitive synthetic double-stranded DNA sequence of poly(dA-dT)•poly(dT-dA) and a synthetic analog of B-DNA. Poly(dA:dT) is recognized by several sensors, including DAI, LRRFIP1 and AIM2.
Poly(dA:dT) is also indirectly detected by RIG-I. The activity of poly(dA:dT) is tested using the reporter cell line B16-Blue™ IFNα/β.
Poly(dA:dT) is complexed with the cationic lipid transfection reagent LyoVec™ to facilitate its uptake.Back to the top
Activity: RIG-I & CDS agonist, AIM2 inflammasome inducer
Formulation: Complexed with the transfection reagent LyoVec™
CAS number: 86828-69-5
Solubility: 2 mg/ml in physiological water
Endotoxin level: EndoFit™ (<0.001 EU/µg)Back to the top
- 4 x 25 μg lyophilized poly(dA:dT)/LyoVec™
- 10 ml sterile endotoxin-free water
Note: Each vial contains 25 μg of poly(dA-dT)•poly(dT-dA) complexed with 50 μg LyoVec.
Poly(dA:dT)/LyoVec™ is provided lyophilized and shipped at room temperature.
Store lyophilized product at -20˚C for up to 12 months .Back to the top