ODN 1668 FITC
|ODN 1668 FITC||Unit size||Cat. code||Docs||Qty||Price|
Class B - FITC-labeled ODN 1668
FITC labeled CpG oligonucleotide - Murine TLR9 ligand
CpG ODNs are synthetic oligonucleotides that contain unmethylated CpG dinucleotides in particular sequence contexts (CpG motifs).
These CpG motifs are present at a 20-fold greater frequency in bacterial DNA compared to mammalian DNA.
They have been shown to induce a coordinated set of immune responses based on the activation of immune cells primarily involved in the recognition of these molecules.
ODN 1668 FITC is a CpG ODN class B specific for murine TLR9.
ODN 1668 FITC can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.Back to the top
Specificity: murine TLR9 agonist
Working concentration: 1 -5 μM
ODN 1668 sequence : 5’-tccatgacgttcctgatgct-3’ (20 mer)
Note: Bases are phosphorothioate (nuclease resistant).
Spectral Properties of FITC
Excitation λ max: 495 nm
Emission λ max: 520 nm
- 50 μg (7.25 nmol) lyophilized ODN1668 labeled with FITC at the 3’ terminus
- 1 ml sterile endotoxin-free water
ODN 1668 FITC is shipped at room temperature.
Store at -20°C. Resuspended product should be stored at -20°C.
Product is stable for 6 months.
Protect from light. Avoid repeated freeze-thaw cycles.Back to the top