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ODN 1668 FITC

ODN 1668 FITC Unit size Cat. code Docs Qty Price
Class B - FITC-labeled ODN 1668
50 µg
tlrl-1668f
+-
$121.00

FITC labeled CpG oligonucleotide - Murine TLR9 ligand

CpG ODNs are synthetic oligonucleotides that contain unmethylated CpG   dinucleotides in particular sequence contexts (CpG motifs).

These CpG motifs are present at a 20-fold greater frequency in bacterial DNA   compared to mammalian DNA.

They have been shown to induce a coordinated   set of immune responses based on the activation of immune cells   primarily involved in the recognition of these molecules.

ODN 1668 FITC is a CpG ODN class B specific for murine TLR9.

ODN 1668 FITC can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.

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Specifications

Specificity: murine TLR9 agonist

Working concentration: 1 -5 μM

ODN 1668 sequence : 5’-tccatgacgttcctgatgct-3’ (20 mer)
Note: Bases are phosphorothioate (nuclease resistant).

Spectral Properties of FITC
Excitation λ max: 495 nm
Emission λ max: 520 nm

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Contents

  • 50 μg (7.25 nmol) lyophilized ODN1668 labeled with FITC at the 3’ terminus
  • 1 ml sterile endotoxin-free water

room temperature ODN 1668 FITC is shipped at room temperature.

store Store at -20°C. Resuspended product should be stored at -20°C.

stable Product is stable for 6 months.

Alert Protect from light. Avoid repeated freeze-thaw cycles.

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