ODN 1668

Class B CpG oligonucleotide - Murine TLR9 ligand

CpG ODNs are synthetic oligonucleotides that contain unmethylated CpG dinucleotides in particular sequence contexts (CpG motifs).

These CpG motifs are present at a 20-fold greater frequency in bacterial DNA compared to mammalian DNA.

CpG ODNs are recognized by Toll-like receptor 9 (TLR9) leading to strong immunostimulatory effects.

ODN 1668 is a CpG ODN class B specific for mouse TLR9. B-class CpG ODNs contain a full phosphorothioate backbone with one or more CpG dinucleotides.

They strongly activate B cells but weakly stimulate IFN-α secretion.

Customer Service
& Technical Support
Contact us
Shopping cart is empty