NF-κB & MAPK Activation Inhibitors

Inhibitors of NK-kB & MAPK Activation Pathway

InvivoGen provides a choice of inhibitors of the nuclear transcription factor NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) and of the MAPKs (mitogen-activated protein kinases).

NF-κB and MAPK pathways regulate the expression of many genes involved in a variety of processes including inflammation, apoptosis, tumorigenesis, and auto-immune diseases.

Several of the PRR (pattern recognition receptors) signaling cascades culminate in the activation of NF-κB transcription factor and /or MAPK.

The inhibitors can be used to dissect these signaling pathways.

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